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New research by the National Heart, Lung, and Blood Institute, the
Center for Cardiovascular Disease Prevention at Baylor College of
Medicine, and other prestigious research facilities has uncovered
new information that might lead to earlier detection of coronary heart
disease (CHD) in patients.
It was previously hypothesized that CHD, the most common form of
heart disease and the number one killer of Americans, was caused
by lipid accumulation within the arterial walls. However, nearly
one half of all patients that suffer from CHD have normal (<130
mg/dL) or even below normal LDL cholesterol levels.
Recent studies have shown that inflammation within the arteries
plays a central role in CHD and heart attacks. For the millions
of patients who fall into the ‘gray area’ between ‘high’
and ‘low’ risk as determined by traditional risk factors,
the identification of additional risk factors is invaluable in determining
their complete CHD risk profile. Inflammatory markers are considered
emerging risk factors that can be used to augment traditional testing
and help identify at-risk patients. The markers C-Reactive Protein
(CRP) and Lipoprotein-associated phospholipase A2 (Lp-PLA2) and
their associated tests (hs-CRP and PLAC) may help the medical community
address the CHD epidemic. More-->
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